NLX-PyIO 1.0 – Python Utilities for Neuralynx Data Import/Export now available

We’re excited to announce the release of NLX-PyIO 1.0, a powerful Python-based utility designed to simplify the import and export of Neuralynx data formats. Built for researchers, data analysts, and developers, NLX-PyIO bridges the gap between Neuralynx acquisition systems and Python-based analysis workflows—bringing modern flexibility to legacy data.

Key Features:
• Support for Neuralynx file types (.ncs, .nse, .nst, .ntt, .nev)
• Pure Python interface with performance-critical routines in Cython
• Easy installation via Python wheel (Python 3.9+, Windows 10/11)
• Designed for both programmers and non-programmers
• Seamless import/export for post-acquisition data workflows


NLX-PyIO empowers you to work directly in Python while maintaining compatibility with existing tools and formats. Mirrors the same functionality as matlab.

You can request software here.